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Updated: Sep 23, 2025
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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
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Ultrafast 30-s total-body PET/CT scan: a preliminary study
Yiqiu Zhang1,2,3, Pengcheng Hu1,2,3, Yibo He1,2,3
1Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai, China.
Summary
Ultrafast 30-second total-body PET/CT scans show diagnostic value for oncology patients. This rapid imaging technique meets clinical needs, especially for those unable to remain still for extended periods.
Area of Science:
- Nuclear Medicine
- Medical Imaging
- Oncology
Background:
- Positron Emission Tomography/Computed Tomography (PET/CT) is crucial in oncology.
- Long acquisition times can limit patient tolerance and image quality.
- Total-body PET/CT offers potential for faster imaging.
Purpose of the Study:
- To evaluate the diagnostic performance of ultrafast 30-second total-body PET/CT imaging.
- To determine if 30-second scans meet clinical diagnostic requirements.
- To compare 30-second scan data with standard 300-second scans.
Main Methods:
- Retrospective analysis of 88 oncology patients.
- Acquisition of total-body PET/CT data over 300 seconds with 18F-FDG.
- Image reconstruction and assessment using 300-second (G300) and 30-second (G30) datasets.
- Comparison of qualitative and quantitative image analysis between G300 and G30.
Main Results:
- G300 showed higher qualitative scores than G30 (P < 0.001).
- Quantitative differences in SUVmax, SD, and SNR were noted in liver and mediastinum (P < 0.001).
- Similar diagnostic sensitivities (89.09% vs. 86.36%) and comparable accuracy and AUC were observed between G300 and G30 (P > 0.05).
Conclusions:
- Thirty-second total-body PET/CT imaging is diagnostically valuable for oncology.
- This ultrafast imaging meets clinical requirements for malignant tumor detection.
- It is particularly beneficial for patients with limited tolerance for prolonged scans.
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