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Influenza vaccination coverage in pediatric population in Italy: an analysis of recent trends
Floriana D'Ambrosio1, Teresa Eleonora Lanza1, Rosaria Messina1
1Section of Hygiene, Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Insights
Pediatric influenza vaccination coverage in Italy remained low over an 11-year period, with a notable increase in the 2020/21 season. Universal vaccination for children is recommended due to high influenza-like illness incidence.
Area of Science:
- Pediatric Public Health
- Vaccinology
- Epidemiology
Background:
- Influenza significantly contributes to global morbidity and mortality, exacerbating chronic conditions.
- Influenza vaccination is crucial for disease burden reduction.
- This study focuses on pediatric influenza vaccination trends in Italy from 2010/11 to 2020/21.
Purpose of the Study:
- To analyze the trend of influenza vaccination coverage in Italian children aged 0-8 years.
- To observe the incidence of influenza-like illness (ILI) in the pediatric population during the study period.
- To inform public health strategies for improving pediatric vaccination rates.
Main Methods:
- Analysis of national and regional influenza vaccination coverage data for children aged <2, 2-4, and 5-8 years.
- Examination of influenza-like illness (ILI) incidence rates in pediatric populations.
- Longitudinal study covering the 2010/11 to 2020/21 influenza seasons.
Main Results:
- Pediatric influenza vaccination coverage remained low between 2010/11 and 2019/20, with highest coverage around 4.5%.
- The 2020/21 season saw a substantial increase in coverage across all age groups, reaching 19.0% in the 2-4 year olds.
- Peak ILI incidence was 18.5% for 0-4 year olds (2011/12) and 27.7% for 5-14 year olds (2010/11).
Conclusions:
- Despite a recent increase, overall pediatric influenza vaccination coverage in Italy has been low over the past decade.
- Universal influenza vaccination for children is warranted due to high disease incidence in this demographic.
- Further research is needed to enhance coverage data comparability and identify effective delivery models.
Background:
Influenza is a major cause of morbidity, mortality and exacerbation of extant chronic disease worldwide. Influenza vaccination is thus fundamental to reduce the burden of disease. In this study, we describe the trend of influenza vaccination coverage in the seasons 2010/11-2020/21 among children aged < 2, 2-4 and 5-8 in Italy.
Methods:
We analyzed the trend of influenza vaccination coverage in the pediatric population in Italy from the 2010/11 to the 2020/21 season at national and regional level and observed the incidence of influenza-like illness (ILI) in the pediatric population between 2010/11 and 2020/21.
Results:
In the period 2010/11-2019/20 the highest value of coverage (4.5%) was reached in the age group 2-4 and 5-8 (season 2010/11 and 2011/12, respectively), while the lowest belonged to the < 2 group (1.1% in the season 2015/16). In the season 2020/2021 all the age groups reported a substantial increase of coverage compared with the previous season. The highest value (19.0%) was reported in the age group 2-4, followed by the group 5-8 and < 2 (13.1 and 9.2%, respectively). Considering the rates of annual ILI cases, the highest value for the 0-4 age group was 18.5% in the 2011/12 season; for the 5-14 age group, the highest value was 27.7% in the 2010/11 season.
Conclusions:
Over the past 11 years pediatric influenza vaccination coverage in Italy has been low, with relevant differences across regions and seasons, albeit a general increase in coverage has been observed in the 2020/21 season. Universal influenza vaccination for children should be considered as a priority for the high incidence in this age group. Further research is needed to improve knowledge and comparability of coverage rates, and to identify the best practices for organizational models of delivery which can support the improvement of trends, the acceptability and accessibility by parents and awareness in stakeholders and decision makers.
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