Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Two postprocessing CT techniques for determining the composition of trabecular bone.

M M Goodsitt, D I Rosenthal, W R Reinus

    Investigative Radiology
    |March 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    International guidelines for the delineation of the postoperative clinical target volumes (CTV) for parotid and submandibular gland cancers.

    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2025
    Same author

    Exploratory Study of Low Resolution Electromagnetic Tomography (LORETA) Real-Time Z-Score Feedback in the Treatment of Pain in Patients with Head and Neck Cancer.

    Brain topography·2018
    Same author

    Italian version of the M.D. Anderson Symptom Inventory--Head and Neck Module: linguistic validation.

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2015
    Same author

    Sonographic examination of the neck after definitive radiotherapy for node-positive oropharyngeal cancer.

    AJNR. American journal of neuroradiology·2011
    Same author

    Osteoradionecrosis of the hyoid bone: imaging findings.

    AJNR. American journal of neuroradiology·2009
    Same author

    Enlargement and transformation of thyroglossal duct cysts in response to radiotherapy: imaging findings.

    AJNR. American journal of neuroradiology·2009
    Same journal

    3D Freehand Ultrasound Imaging of Optic Nerve Sheath.

    Investigative radiology·2026
    Same journal

    Iodinated Contrast Media Hypersensitivity in 115,966 Patients: Risk Factors, Severity Profiles, and the Impact of Iodine Concentration on Reaction Risk.

    Investigative radiology·2026
    Same journal

    Improvement of Lung Nodule Volumetric Accuracy with Photon-counting Computed Tomography Over Energy-integrating Computed Tomography in Low-dose Screening: A Phantom Study.

    Investigative radiology·2026
    Same journal

    Photon-counting CT in Anterior Cervical Discectomy and Fusion: Improved Metal Artifact Reduction and Impact on Bone Fusion Assessment.

    Investigative radiology·2026
    Same journal

    Quantitative Synthetic MRI in Body Imaging: Technical Basis, Current Applications, and Future Directions.

    Investigative radiology·2026
    Same journal

    Nonclinical Safety Assessment of Digadoglucitol, a Novel Magnetic Resonance Imaging Contrast Agent for the Central Nervous System.

    Investigative radiology·2026
    See all related articles

    New dual-energy CT methods accurately assess bone mineral and fat content. These techniques offer improved bone disease analysis, including osteoporosis, by separately estimating fat composition.

    Area of Science:

    • Radiology
    • Biomedical Engineering
    • Orthopedics

    Background:

    • Trabecular bone analysis is crucial for understanding bone health and diseases like osteoporosis.
    • Accurate assessment of both mineral and fat content in bone is challenging with conventional methods.

    Purpose of the Study:

    • To develop and evaluate novel dual-energy CT (DECT) postprocessing techniques for analyzing trabecular bone mineral and fat content.
    • To compare the performance of these new DECT methods against conventional single-energy CT and existing DECT techniques.

    Main Methods:

    • Development of two new DECT postprocessing algorithms utilizing calibration standards.
    • Experimental validation of the new techniques against established CT methods using phantom or ex vivo bone samples.
    • Assessment of accuracy in estimating bone mineral content in the presence of varying fat fractions.

    Related Experiment Videos

    Main Results:

    • All tested DECT methods improved mineral content accuracy when bone fat was present compared to single-energy CT.
    • The novel DECT techniques demonstrated unique capability in separately estimating bone fat content.
    • Preliminary fat content estimations showed encouraging trends, correlating positively with increasing fat fractions.

    Conclusions:

    • The developed DECT techniques offer a promising approach for more accurate bone composition analysis.
    • These methods have potential applications in the research and clinical study of osteoporosis and other metabolic bone diseases.
    • Separate estimation of bone fat content by DECT provides valuable insights beyond mineral density measurements.