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Updated: Sep 23, 2025

Imaging of the Microstructural Failure Mechanism in the Human Hip
Published on: September 29, 2023
Biomechanical structure-function relations for human trabecular bone - comparison of calcaneus, femoral neck, greater
Saghi Sadoughi1, Grant Bevill2, Elise F Morgan3
1Department of Mechanical Engineering, University of California, Berkeley, CA.
Abstract:
MicroCT-based finite element models were used to compute power law relations for uniaxial compressive yield stress versus bone volume fraction for 78 cores of human trabecular bone from five anatomic sites. The leading coefficient of the power law for calcaneus differed from those for most of the other sites (p < 0.05). However, after normalizing by site-specific mean values, neither the leading coefficient (p > 0.5) nor exponent (p > 0.5) differed among sites, suggesting that a given percentage deviation from mean bone volume fraction has the same mechanical consequence for all sites investigated. These findings help explain the success of calcaneal x-ray and ultrasound measurements for predicting hip fracture risk.
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