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Related Concept Videos

Randomized Experiments01:13

Randomized Experiments

7.9K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
7.9K
Blinding01:11

Blinding

3.2K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
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Related Experiment Video

Updated: Sep 23, 2025

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
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Rapid centralised randomisation in emergency setting trials using a smartphone.

Shiraz Badurdeen1,2, Kate A Hodgson3,4, Georgia A Santomartino1

  • 1Newborn Research Centre, The Royal Women's Hospital, 20 Flemington Rd, Parkville, VIC, 3052, Australia.

European Journal of Pediatrics
|May 17, 2022
PubMed
Summary
This summary is machine-generated.

Rapid randomisation for emergency trials is crucial. A smartphone-based REDCap platform enabled quick, reliable participant allocation in neonatal resuscitation trials, proving effective for urgent clinical research settings.

Keywords:
NeonatalRandomised controlled trial

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Area of Science:

  • Clinical Trials Methodology
  • Emergency Medicine
  • Neonatal Care

Background:

  • Randomised trials in emergency settings require swift participant eligibility confirmation and intervention allocation.
  • Treatment delays must be avoided during emergency trial randomisation processes.

Purpose of the Study:

  • To evaluate a novel, non-commercial, smartphone-accessible platform for rapid randomisation in emergency settings.
  • To assess the reliability and efficiency of bedside randomisation during neonatal resuscitation trials.

Main Methods:

  • Utilised the REDCap platform accessed via smartphone for participant randomisation.
  • Implemented the method during two concurrent neonatal resuscitation trials in an emergency setting.

Main Results:

  • The smartphone-based REDCap platform facilitated rapid and accurate participant randomisation at the bedside.
  • The system proved to be a simple and reliable tool for emergency trial logistics.

Conclusions:

  • Smartphone-accessible REDCap offers a viable solution for rapid randomisation in time-sensitive emergency research.
  • This approach has broad applicability for improving the efficiency of clinical trials conducted in emergency environments.