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Morphological parameters predicting subthreshold micropulse laser effectiveness in central serous chorioretinopathy.
Peter Kiraly1,2, Jaka Smrekar3, Polona Jaki Mekjavić4,5,6
1Eye Hospital, University Medical Centre Ljubljana, 1000, Ljubljana, Slovenia.
Lasers in Medical Science
|May 17, 2022
Summary
Subthreshold micropulse laser (SML) is effective for central serous chorioretinopathy (CSC). Lower subretinal fluid, narrower pigment epithelial detachment, and fewer hyperreflective foci predict a good SML response in CSC patients.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Medical Imaging
Background:
- Central serous chorioretinopathy (CSC) is a condition affecting vision.
- Subthreshold micropulse laser (SML) is a treatment option for persistent CSC.
- Predicting SML effectiveness is crucial for patient management.
Purpose of the Study:
- To predict the effectiveness of subthreshold micropulse laser (SML) in patients with central serous chorioretinopathy (CSC).
- To identify morphological parameters that correlate with SML treatment outcomes.
Main Methods:
- Prospective study of 31 CSC patients.
- Morphological parameters assessed using multimodal imaging before SML treatment.
- Parameters included subretinal fluid (SRF), pigment epithelial detachment (PED) width, and hyperreflective foci (HF).
Main Results:
- Good SML response was associated with lower SRF, narrower PED, and fewer hyperreflective foci at the fovea.
- Multivariate analysis showed significant differences based on combinations of SRF, PED width, and hyperreflective foci.
Conclusions:
- Lower SRF, narrower PED, and decreasing HF are potential predictors of good SML response in CSC.
- Morphological assessment can aid in tailoring SML treatment for CSC.
