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A new Down syndrome rat model races forward
Randall J Roper1, Charles R Goodlett2
1Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Trends in Genetics : TIG
|May 17, 2022
Abstract:
Animal models of Down syndrome (DS) provide an essential resource for understanding genetic, cellular, and molecular contributions to traits associated with trisomy 21 (Ts21). Recent genetic enhancements in the development of DS models, including the new TcHSA21rat model (Kazuki et al.), have potential to transform our understanding of and potential therapies for Ts21.
