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Updated: Sep 23, 2025

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Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL

Paloma García-Martín1, Ana Moñiz Díez2,3,4, José Manuel Sánchez Maldonado2,3,4

  • 1Hospital Campus de la Salud, PTS Granada, Granada, Spain.

Blood Cancer Journal
|May 17, 2022
PubMed
Abstract

No abstract available in PubMed .

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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