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Diffuse Large B-Cell Lymphoma - Rare Presentation.

Rodrigo Cordeiro¹, Mariana Chaves¹

¹Hospital do Divino Espírito Santo de Ponta Delgada, PT.

Journal of the Belgian Society of Radiology

|May 18, 2022

Summary

This summary is machine-generated.

Subcutaneous nodules without skin involvement are a rare sign of diffuse large B-cell lymphoma (DLBCL). This finding highlights an unusual presentation of this aggressive blood cancer.

Keywords:

B-cell lymphoma CT diffuse large B-cell lymphoma subcutaneous tissue ultrasound

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Area of Science:

Oncology
Dermatology
Hematology

Background:

Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
DLBCL typically presents with lymphadenopathy or extranodal disease.

Observation:

This case presents a rare manifestation of DLBCL.
The patient exhibited subcutaneous nodules.
These nodules specifically spared the dermis and showed no extracutaneous involvement.

Findings:

The subcutaneous nodules were histopathologically confirmed as DLBCL.
This presentation is atypical for DLBCL, which commonly involves lymph nodes or other organs.

Implications:

Recognizing rare presentations of DLBCL is crucial for timely diagnosis and treatment.
This case expands the spectrum of clinical manifestations for DLBCL.
Further research may elucidate the mechanisms behind this specific presentation.