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Myriad Presentations of Intracranial Meningiomas: Pictoral Essay
1Armed Forces Medical College, Pune, IN.
Abstract:
Meningiomas are the most common non-glial tumor of the central nervous system (CNS). Seen in middle age with a female preponderance, most of the tumors are solitary and supratentorial with benign histology (WHO grade I). Atypical and anaplastic (malignant) meningiomas (WHO grade II and III), comprise 15-20% of all intracranial meningiomas [12345]. Magnetic resonance imaging (MRI) is the imaging modality of choice.
Insights
Meningiomas are common brain tumors, mostly benign but some malignant. Magnetic resonance imaging (MRI) is the preferred diagnostic tool for these central nervous system (CNS) tumors.
Area of Science:
- Neuro-oncology
- Central Nervous System (CNS) Tumors
- Neurosurgery
Background:
- Meningiomas represent the most frequent non-glial tumors affecting the central nervous system.
- These tumors predominantly occur in middle-aged individuals, with a notable female predilection.
- The majority of meningiomas are solitary, supratentorial, and exhibit benign histology (WHO grade I).
Observation:
- A significant minority, 15-20%, are atypical or anaplastic (malignant) meningiomas (WHO grade II and III).
- These higher-grade tumors indicate a more aggressive disease course.
- The abstract highlights the need for accurate classification and management strategies.
Findings:
- While most meningiomas are benign, the presence of atypical and anaplastic subtypes necessitates careful evaluation.
- The prevalence of WHO grade II and III meningiomas underscores the spectrum of meningioma behavior.
- Further research may elucidate factors distinguishing benign from malignant presentations.
Implications:
- Accurate diagnosis and grading of meningiomas are crucial for appropriate treatment planning.
- Understanding the incidence of malignant subtypes informs prognostic assessments.
- Magnetic resonance imaging (MRI) is established as the primary imaging modality for diagnosing meningiomas.
