Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Heredity and overfeeding-induced changes in submaximal exercise VO2.

A Tremblay, E T Poehlman, A Nadeau

    Journal of Applied Physiology (Bethesda, Md. : 1985)
    |February 1, 1987
    PubMed
    Summary

    Heredity influences how your body adapts its energy expenditure during exercise after overfeeding. Genetic factors play a significant role in how individuals respond to increased calorie intake, affecting fat storage and energy use.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Relation between grip strength of independent elders and functional decline following an emergency department visit : a pan-Canadian study].

    Revue medicale de Liege·2021
    Same author

    Stress in Parents of Children With Genetically Determined Leukoencephalopathies: A Pilot Study.

    Journal of child neurology·2020
    Same author

    Influence of aerobic exercise training on the neural correlates of motor learning in Parkinson's disease individuals.

    NeuroImage. Clinical·2016
    Same author

    Enhancing both motor and cognitive functioning in Parkinson's disease: Aerobic exercise as a rehabilitative intervention.

    Brain and cognition·2015
    Same author

    Prevalence of colonic motor or evacuation disorders in patients presenting with chronic nausea and vomiting evaluated by a single gastroenterologist in a tertiary referral practice.

    Neurogastroenterology and motility·2013
    Same author

    Interpretation of overall colonic transit in defecation disorders in males and females.

    Neurogastroenterology and motility·2013

    Area of Science:

    • Exercise Physiology
    • Human Genetics
    • Metabolic Adaptation

    Background:

    • Understanding the factors influencing adaptive thermogenesis is crucial for managing body weight and metabolic health.
    • Previous research suggests individual variability in energy expenditure responses to overfeeding.
    • The role of genetic predisposition in these adaptive responses remains incompletely understood.

    Purpose of the Study:

    • To investigate the heritability of changes in exercise energy cost following short-term overfeeding.
    • To explore the relationship between genetic factors, sympathoadrenal activity, and adaptive thermogenesis.
    • To determine if the body's ability to adjust exercise energy expenditure to overfeeding is inherited.

    Main Methods:

    • Studied six pairs of monozygotic twins undergoing a controlled 1,000 kcal/day surplus for 22 days.

    Related Experiment Videos

  • Measured oxygen consumption (VO2) during submaximal treadmill exercise pre- and post-overfeeding.
  • Analyzed changes in body weight, fat mass, blood catecholamines, and exercise VO2.

    • Main Results:

    • Overfeeding increased body weight and fat mass, but mean exercise VO2 did not significantly change.
    • Significant interindividual variation in exercise VO2 response to overfeeding was observed.
    • A moderate to high within-pair resemblance in VO2 response suggested a genotype-overfeeding interaction.
    • Changes in exercise VO2 correlated positively with epinephrine levels and negatively with body fat gain.

    Conclusions:

    • The sensitivity to adapt exercise energy expenditure after overfeeding is significantly heritable.
    • The sympathoadrenal system plays a role in regulating adaptive thermogenesis and fat storage.
    • Genetic factors influence individual responses to overfeeding, impacting energy expenditure and fat accumulation.