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Updated: Sep 22, 2025

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
Published on: August 24, 2017
Exploring the effect of neurofeedback on postcancer cognitive impairment and fatigue: A pilot feasibility study
Marian Luctkar-Flude1, Jane Tyerman2, Shawna Burnett3
1Queen's University, School of Nursing, 92 Barrie St. Kingston, ON, K7L 3N6, 613-533-6000 Ext. 77383; mfl1@queensu.ca, https://www.linkedin.com/in/marian-luctkar-flude-1201642a/, https://twitter.com/marianlflude.
Purpose:
Postcancer cognitive impairment (PCCI) and fatigue are adverse effects that often persist following cancer treatment, and impact quality of life. The study purpose was to evaluate feasibility and effect of neurofeedback on cognitive functioning and fatigue in cancer survivors. Specifically, we aimed to test feasibility of recruitment strategies and our study protocol including outcome measures.
Design:
This pilot feasibility study used a 10-week wait-list design. Participants served as their own controls and received neurofeedback training twice a week for 10 weeks.
Participants:
The sample consisted of breast cancer survivors from Kingston, Ontario (n = 16).
Methods:
Outcomes were assessed using validated, self-report scales and neuropsychological tests before, during, and after neurofeedback.
Findings:
The neurofeedback protocol was feasible and resulted in significant decreases in perceived cognitive deficits, fatigue, sleep, and psychological symptoms.
Implications For Psychosocial Providers:
Neurofeedback may be an effective, non-invasive complementary therapy for PCCI in breast cancer survivors.

