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Updated: Sep 22, 2025

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

Cardiac myxomas: A narrative review.

A K M Monwarul Islam¹

¹Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka 1207, Bangladesh. drmonwarbd@yahoo.com.

World Journal of Cardiology

|May 18, 2022

Summary

Cardiac myxomas, benign heart tumors, pose risks due to embolization. Early diagnosis via echocardiography and surgical removal are crucial for preventing serious complications and ensuring good outcomes.

Area of Science:

Cardiology
Oncology
Pathology

Background:

Cardiac myxomas are primary heart tumors, often benign but functionally malignant due to embolization risk.
They commonly arise in the left atrium but can occur in any chamber, presenting sporadically or as part of Carney complex.
Morphological variations (polypoid, papillary) influence clinical presentation, with papillary forms more prone to embolization.

Purpose of the Study:

To review the epidemiology, pathogenesis, clinical presentation, diagnosis, and management of cardiac myxomas.
To highlight the diagnostic utility of echocardiography and other imaging modalities.
To emphasize the importance of timely surgical intervention for favorable outcomes.

Main Methods:

Review of existing literature on cardiac myxomas.

Keywords:

Cardiac Carney Complex Echocardiography Embolism Myxoma Neoplasm

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Analysis of clinical presentations, diagnostic findings, and treatment outcomes.

Discussion of histopathological and genetic aspects.

Main Results:

Cardiac myxomas present with intracardiac obstruction, embolic events, and constitutional symptoms.
Echocardiography is the primary diagnostic tool, revealing characteristic mobile masses.
Surgical excision offers low operative mortality, high survival rates, and low recurrence.

Conclusions:

Cardiac myxomas require prompt diagnosis and surgical management to prevent life-threatening complications.
Minimal-access surgery is the current trend, improving patient outcomes.
Understanding the diverse presentations and diagnostic features is key for effective physician preparedness.