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Updated: Sep 22, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
[Systemic and extrapulmonary manifestations of COVID-19]
J Balsa Vázquez1, D Alonso Menchén1, M M Martín Lloréns1
1Servicio de Medicina Interna. Hospital Universitario Príncipe de Asturias. Universidad de Alcalá. Alcalá de Henares. Madrid. España.
COVID-19 can cause serious extrapulmonary complications affecting multiple organs, not just the lungs. Early diagnosis and individualized treatment are crucial for managing these systemic effects and ensuring patient recovery.
Area of Science:
- * Explores the diverse extrapulmonary manifestations of COVID-19.
- * Highlights the role of Angiotensin-Converting Enzyme 2 (ACE2) receptors in viral entry and multisystemic involvement.
Context:
- * While fever and respiratory symptoms are primary, COVID-19 frequently leads to significant complications in other organ systems.
- * Systemic effects can precede, accompany, or follow typical respiratory symptoms, impacting various bodily functions.
Purpose:
- * To detail the range of systemic complications associated with COVID-19.
- * To discuss diagnostic approaches and therapeutic considerations for extrapulmonary manifestations.
- * To address specific concerns regarding pregnant women and children.
Summary:
- * COVID-19 causes multisystemic involvement due to widespread ACE2 receptor distribution.
- * Thromboembolic events are a significant concern, stemming from a hypercoagulable state.
- * Cardiac, neurological, gastrointestinal, renal, endocrine-metabolic, skin, and ocular systems can be affected.
Impact:
- * Emphasizes the need for comprehensive diagnostic testing based on clinical suspicion.
- * Stresses individualized treatment strategies, often similar to those for the general population.
- * Provides insights into managing COVID-19 complications in specific populations like pregnant women and children.
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