Related Experiment Video

Updated: Sep 22, 2025

A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors
09:04

A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors

Published on: March 15, 2016

9.8K

An appraisal of vascular endothelial growth factor (VEGF): the dynamic molecule of wound healing and its current

Aakansha Giri Goswami1, Somprakas Basu1, Farhanul Huda1

  • 1Department of General surgery, All India Institute of Medical Sciences, Rishikesh, India.

Growth Factors (Chur, Switzerland)
|May 18, 2022
PubMed

Keywords:
Vascular endothelial growth factorangiogenesisdiabetic ulcerperipheral arterial diseasevenous ulcerwound healing

More Related Videos

Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay08:43

Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay

Published on: June 19, 2018

15.1K
Author Spotlight: Investigating Angiogenesis Through Challenges and Innovations in Assay Development09:16

Author Spotlight: Investigating Angiogenesis Through Challenges and Innovations in Assay Development

Published on: May 31, 2024

1.5K

Related Concept Videos

Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
2.8K
Mechanism of Angiogenesis01:10

Mechanism of Angiogenesis

Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...
6.0K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.8K