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Updated: Sep 22, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
Beyond technology: Can artificial intelligence support clinical decisions in the prediction of sepsis?
Juliane de Souza Scherer1, Jéssica Silveira Pereira1, Mariana Severo Debastiani1
1Universidade Federal de Ciências da Saúde de Porto Alegre. Porto Alegre, Rio Grande do Sul, Brazil.
Objective:
To analyze the critical alarms predictors of clinical deterioration/sepsis for clinical decision making in patients admitted to a reference hospital complex.
Methods:
An observational retrospective cohort study. The Machine Learning (ML) tool, Robot Laura®, scores changes in vital parameters and lab tests, classifying them by severity. Inpatients and patients over 18 years of age were included.
Results:
A total of 122,703 alarms were extracted from the platform, classified as 2 to 9. The pre-selection of critical alarms (6 to 9) indicated 263 urgent alerts (0.2%), from which, after filtering exclusion criteria, 254 alerts were delimited for 61 inpatients. Patient mortality from sepsis was 75%, of which 52% was due to sepsis related to the new coronavirus. After the alarms were answered, 82% of the patients remained in the sectors.
Conclusions:
Far beyond technology, ML models can speed up assertive clinical decisions by nurses, optimizing time and specialized human resources.
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