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Conditions Affecting Social Space in Drosophila melanogaster
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Isolation disrupts social interactions and destabilizes brain development in bumblebees.

Z Yan Wang1, Grace C McKenzie-Smith2, Weijie Liu3

  • 1Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA; Lewis Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ, USA.

Current Biology : CB
|May 18, 2022
PubMed
Summary

Early social isolation in bumblebees alters social behavior and brain development. Limited group experience preserves normal social interactions and neuroanatomy.

Keywords:
RNA-seqantennationbraingene expressionmachine visionsocial behaviorsocial insectssocial isolation

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Area of Science:

  • Behavioral Ecology
  • Neuroscience
  • Insect Social Behavior

Background:

  • Early life social isolation can negatively impact physiological and behavioral outcomes.
  • Understanding the neurobiological underpinnings of social behavior is crucial.

Purpose of the Study:

  • To investigate the effects of social isolation on bumblebee behavior, gene expression, and brain development.
  • To identify the neurobiological correlates of isolation-induced behavioral changes.

Main Methods:

  • Rearing bumblebees (Bombus impatiens) in isolation, small groups, or natal colonies.
  • Analyzing social behaviors when bees were alone or paired with a conspecific.
  • Quantifying brain gene expression and measuring key brain region volumes.

Main Results:

  • Isolated bees exhibited distinct behavioral signatures when alone and increased social interactions when paired.
  • Bees reared in groups or colonies showed similar social behaviors, unlike isolated individuals.
  • Social isolation led to disruptions in gene expression and brain development.

Conclusions:

  • Early social isolation in bumblebees significantly impacts social behavior and neurobiology.
  • Limited social experience, even in small groups, is sufficient to maintain typical social behavior and brain development.
  • These findings highlight the critical role of early social environment in shaping an individual's sociality and neural architecture.