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Published on: February 28, 2012
Superwarfarin poisoning: challenges still remain
Ariadna de Genover Gil1, Gabriel Manuel Gonzalez Suarez2, Carla Moret Puig3
1Internal Medicine, Doctor Josep Trueta University Hospital of Girona, Girona, Spain agenover.girona.ics@gencat.cat.
Abstract:
Superwarfarin (long-acting anticoagulant rodenticide) poisoning should be suspected in unexplained bleeding with prolonged prothrombin time, especially in the absence of another explanation. Diagnosis and treatment of this intoxication remain a challenge as the direct analysis of superwarfarin in serum is not always possible. Therefore, toxin bioavailability remains unknown and close monitoring and treatment for long periods are required to avoid serious bleeding complications. Here, we discuss a case of suspected superwarfarin poisoning to highlight the challenges in early diagnosis and the challenges we encountered in treatment management and ensuring compliance for long periods.
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