Separation of proteins on a polymeric fluorocarbon high-performance liquid chromatography column packing

A rigid, inert fluorocarbon resin has been evaluated as an high-performance liquid chromatography packing for the separation of proteins and peptides. Samples are separated with gradient elution of the mobile phase from aqueous buffer to acetonitrile. The selectivity and retention of the fluorocarbon resin packing for proteins are similar to that of aliphatic hydrocarbon-bonded silica packings.