Multidisciplinary Effort to Drive Precision-Medicine for the Future

Area of Science:

• Genomics
• Translational Research
• Bioinformatics

Background:

• The global shift towards precision medicine (PM) necessitates robust data infrastructure.
• Singapore's National Precision Medicine (NPM) program (est. 2017) is advancing to create a large genomic database for Asians.
• The National University of Singapore (NUS) launched a PM translational research program (TRP) in 2021.

Purpose of the Study:

• To consolidate multidisciplinary expertise for PM initiatives.
• To identify and validate novel therapeutic targets.
• To establish frameworks for data handling and interpretation in PM.

Main Methods:

• Leveraging omics-based technologies.
• Developing collaborative, multidisciplinary research projects.
• Implementing appropriate data collection, processing, and interpretation protocols.

Main Results:

• Singapore is building a significant genomic database for Asian populations.
• NUS is fostering cross-disciplinary collaboration for PM.
• Progress is being made in addressing challenges in PM data management.

Conclusions:

• The era of precision medicine requires advanced data strategies.
• Continuous technological development and regulatory improvements are key to overcoming PM challenges.
• Successful implementation of PM will enable precise disease prediction, diagnosis, treatment, and prevention.