Related Experiment Video
Updated: Sep 22, 2025

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
GraphQL for the delivery of bioinformatics web APIs and application to ZincBind
Sam M Ireland1, Andrew C R Martin1
1Division of Biosciences, Institute of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.
GraphQL offers a new way to access bioinformatics data via web services, improving upon older methods like SOAP and REST. Its graph-based approach allows flexible querying for enhanced data retrieval and analysis.
Area of Science:
- Bioinformatics
- Web Services
- Data Access
Background:
- Bioinformatics resources are often accessed via web services using HTTP.
- Programmatic access is enabled by web application programming interfaces (APIs) returning data formats like XML, JSON, or plain text.
- Traditional API approaches include Simple Object Access Protocol (SOAP) and Representational State Transfer (REST).
Purpose of the Study:
- To review the principles of GraphQL.
- To outline GraphQL's suitability for delivering bioinformatics resources.
- To describe the implementation of GraphQL in the ZincBind resource.
Main Methods:
- Review of GraphQL principles.
- Assessment of GraphQL for bioinformatics resource delivery.
- Implementation of GraphQL in the ZincBind web service.
Main Results:
- GraphQL is a novel alternative to REST and SOAP for web services.
- GraphQL represents data as a graph, allowing flexible querying.
- The ZincBind resource has been implemented using GraphQL.
Conclusions:
- GraphQL presents a powerful and flexible alternative for accessing bioinformatics data.
- Its adoption in industry and suitability for bioinformatics resources are increasing.
- The ZincBind resource demonstrates a practical implementation of GraphQL for scientific data delivery.
More Related Videos
09:10A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
Published on: May 22, 2018
09:52A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease
Published on: January 10, 2025
Related Concept Videos
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Globular and Fibrous Proteins
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...