Related Experiment Video
Updated: Sep 22, 2025

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Renal Interstitial Invasion by Group A Streptococcus: A Rare Presentation
Francis Lomanta1, Shankar Upadhyayula2
1Department of Pediatrics, Akron Childrens Hospital, Akron, OH, USA.
Abstract:
We report the case of a 5-year-old who had interstitial invasion of his kidneys with group A Streptococcus (GAS). Glomeruli and tubules were relatively preserved. He recovered from this event and was admitted a couple of months later with dilated cardiomyopathy needing a heart transplant. To our knowledge, this is the first reported case of direct invasion of renal interstitium by GAS.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pyelonephritis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Rheumatic Heart Disease I: Introduction
Endocarditis I: Introduction
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

