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Updated: Sep 22, 2025

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Use of Cannabis Does Not Decrease Opioid Consumption in Patients Who Underwent Total Joint Arthroplasty.

Jason M Jennings1,2, D Clinton McNabb3, Roseann M Johnson1

  • 1Colorado Joint Replacement, Porter Adventist Hospital, Denver, CO, USA.

Arthroplasty Today
|May 19, 2022
PubMed
Summary
This summary is machine-generated.

Cannabis use did not reduce narcotic consumption in patients undergoing total joint arthroplasty (TJA). This study found no significant difference in pain medication needs between cannabis users and non-users after joint replacement surgery.

Keywords:
CannabinoidsMarijuanaNarcoticsOpioidTotal knee arthroplasty

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Area of Science:

  • Orthopedic Surgery
  • Pain Management
  • Cannabinoid Research

Background:

  • Total joint arthroplasty (TJA) is a common surgical procedure.
  • Managing postoperative pain and opioid consumption is a critical aspect of TJA recovery.
  • The role of cannabis in modulating pain and opioid requirements post-TJA remains an area of investigation.

Purpose of the Study:

  • To investigate whether cannabis use is associated with reduced narcotic consumption in patients undergoing primary unilateral total joint arthroplasty.
  • To assess the impact of self-reported cannabis use on postoperative pain medication requirements and patient-reported pain levels.

Main Methods:

  • Prospective enrollment of 46 patients undergoing primary unilateral TJA who self-reported cannabis use.
  • Matching the cannabis-using cohort with non-using patients for comparison.
  • Quantifying and comparing postoperative narcotic consumption (morphine equivalents) at 1 and 2 weeks, as well as pain scores.

Main Results:

  • No significant differences in morphine equivalents (MEs) were observed during hospitalization or at 1 and 2 weeks postoperatively between cannabis users and non-users.
  • Cannabis users reported significantly higher pain scores at 1 week postoperatively (P=.05).
  • No significant differences were found in pain scores at other time points or in secondary outcomes and complications.

Conclusions:

  • This study did not demonstrate a decrease in narcotic consumption among patients using cannabis undergoing primary unilateral joint replacement.
  • The findings do not support the routine use of cannabis to reduce or supplement narcotic use after primary TJA.
  • Further research may be warranted to explore potential nuanced effects or specific patient populations.