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Efficient method for whole-breast irradiation therapy using Halcyon linear accelerators.

Yi-Chun Tsai1,2, Chia-Chun Wang2, Chun-Wei Wang1

  • 1Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.

Journal of Applied Clinical Medical Physics
|May 19, 2022
PubMed
Summary
This summary is machine-generated.

A new hybrid radiotherapy method for whole-breast irradiation significantly reduces treatment time on the Halcyon accelerator. This approach offers comparable dose statistics to traditional methods, improving efficiency for breast cancer patients.

Keywords:
HalcyonIMRTbreastefficientfield-in-fieldhybrid

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Area of Science:

  • Radiation oncology
  • Medical physics

Background:

  • The Halcyon linear accelerator offers a simplified workflow with a 6-MV flattening filter-free (FFF) beam.
  • Its beam may limit conventional radiotherapy techniques for breast cancer, such as field-in-field (FiF).

Purpose of the Study:

  • To develop and evaluate a practical, efficient hybrid method for whole-breast irradiation using Halcyon accelerators.
  • To assess the feasibility of this method for early-stage breast cancer treatment.

Main Methods:

  • A five-step hybrid method involving field arrangement, PTV generation, basal plan creation, IMRT optimization, and plan evaluation.
  • Utilized tangential fields for PTV generation and a basal-dose-compensation approach for plan optimization.
  • Compared the method's performance against a dynamically flattened beam-based FiF (DFB-FiF) method in 10 patients.

Main Results:

  • The hybrid method achieved comparable dose statistics to DFB-FiF, with homogeneity indices of 0.053 (0.056) vs. 0.073 (0.076).
  • Normal tissue doses (contralateral breast, heart, lungs) were similar between methods.
  • Irradiation time per monitor unit was approximately five times faster with the hybrid method.

Conclusions:

  • The developed hybrid method is practical and efficient for whole-breast irradiation on Halcyon accelerators.
  • This method significantly reduces irradiation time while maintaining comparable dose statistics to DFB-FiF, enhancing treatment efficiency.