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Updated: Sep 22, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
Post-healing follow-up study of patients in remission for diabetic foot ulcers Pied-REM study
Marie Bouly1, Francois-Xavier Laborne2, Caroline Tourte2
1Diabetology Department, Centre Hopitalier Sud Francilien, Corbeil-Essonnes, France.
Abstract:
The rate of recurrence for diabetic foot ulcer (DFU) is 50% at 2 years Armstrong DG, 2017. International recommendations call for regular monitoring to prevent DFU recurrence. We aim to investigate the relation between post-healing follow-up and recurrence rates. The study will begin in November 2021 and end in April 2022; final study results are scheduled for December 2022. The purpose of the study is to evaluate the benefit of the multidisciplinary follow-up of healed DFU patients at the rate of two annual consultations and its impact on foot wound recurrence.
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