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Streptococcus milleri and second trimester abortion
Journal of Clinical Pathology
|March 1, 1987
Abstract:
Review of 214 fetal necropsies performed in the department of pathology, University of Aberdeen, showed 40 cases of chorioamnionitis or intrauterine pneumonia, five of which were associated with Streptococcus milleri. In two cases there was good evidence to implicate S milleri as the cause of infected abortion while in the other cases its pathogenic role was less clear.
Insights
Streptococcus milleri was identified in five cases of chorioamnionitis or intrauterine pneumonia among 214 fetal necropsies. This bacterium showed clear pathogenic potential in two cases of infected abortion.
Area of Science:
- Medical Microbiology
- Perinatal Pathology
Background:
- Chorioamnionitis and intrauterine pneumonia are significant causes of fetal and neonatal morbidity.
- The role of specific bacterial species in these infections requires further elucidation.
Purpose of the Study:
- To investigate the incidence and pathogenic role of Streptococcus milleri in fetal infections.
Main Methods:
- Retrospective review of 214 fetal necropsy records.
- Identification of cases with chorioamnionitis or intrauterine pneumonia.
- Analysis of Streptococcus milleri association and clinical evidence.
Main Results:
- 40 cases of chorioamnionitis/intrauterine pneumonia were identified.
- Streptococcus milleri was detected in five of these cases.
- S. milleri was strongly implicated in two cases of infected abortion; its role was less clear in others.
Conclusions:
- Streptococcus milleri can be a causative agent in fetal infections, including infected abortion.
- Further research is warranted to fully understand the pathogenic mechanisms of S. milleri in perinatal infections.