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Updated: Sep 22, 2025

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
Published on: February 16, 2015
Quantity versus quality: Keys to adoptive cell therapy success in breast cancer
1Masonic Cancer Center and Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.
Abstract:
Over decades, reports of autologous tumor-infiltrating lymphocytes inducing partial and even complete responses in treatment-refractory tumors has spurred investigation into methods for refining and improving this process. Zacharias et al.1 report two partial and one complete response from a phase II study utilizing neoantigen-reactive TILs in patients with metastatic breast cancer.
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