Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

62
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
62
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

39
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
39

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Helical nanoplatelet superlattices assembled from green emissive CsPbI<sub>3</sub> nanoplatelets.

Chemical communications (Cambridge, England)·2026
Same author

One-dimensional CsPbBr<sub>3</sub> superlattices with polarized and amplified spontaneous circularly polarized emissions.

Nature communications·2026
Same author

A chromosome-level genome assembly of the Tristram's Bunting (Emberiza tristrami).

Scientific data·2026
Same author

Multi-omics identifies a T2DM-associated immune-regulatory network modulated by electroacupuncture.

Frontiers in endocrinology·2026
Same author

Seasonal variation in activity rhythms of leopard cats (Prionailurus bengalensis), their prey and competitors in southern Anhui.

Scientific reports·2026
Same author

Correction: CLC3 regulates V-ATPase to enhance lysosomal degradation and cisplatin resistance in cervical cancer cells.

Cell death discovery·2026

Related Experiment Video

Updated: Sep 22, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.8K

Left atrial phasic function remodeling during its enlargement: a two-dimensional speckle-tracking echocardiography

Chuyun Chen1, Ying Yang2,3, Wei Ma1,4

  • 1Department of Cardiology, Peking University First Hospital, 8 Xishiku St, Xicheng District, Beijing, 100034, China.

BMC Cardiovascular Disorders
|May 19, 2022
PubMed
Summary

Left atrial remodeling affects function before enlargement. Two-dimensional speckle-tracking echocardiography reveals impaired reservoir and contractile function in early stages, even with normal left atrial size.

Keywords:
Atrial functionHypertensionLeft atrial remodelingPhasic functionSpeckle tracking

More Related Videos

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

19.8K
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.1K

Related Experiment Videos

Last Updated: Sep 22, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.8K
Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

19.8K
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.1K

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Physiology

Background:

  • Left atrial (LA) size is a common but imperfect surrogate for LA function.
  • A gold standard for assessing LA function is lacking.
  • The relationship between LA size and phasic function, and the timing of dysfunction relative to enlargement, remain understudied.

Purpose of the Study:

  • To investigate the relationship between left atrial size and phasic function.
  • To determine if left atrial dysfunction precedes left atrial enlargement (LAE).
  • To evaluate the utility of 2D speckle-tracking echocardiography (2D STE) in assessing LA function.

Main Methods:

  • A cohort of 715 high-risk cardiovascular disease subjects underwent comprehensive echocardiography.
  • Off-line 2D STE was used to measure LA longitudinal phasic strain: Sa (contractile), Se (conduit), and Stot (reservoir).
  • Data were analyzed across different LA size groups and within normal LA size subgroups with and without hypertension.

Main Results:

  • Total atrial strain (Stot) and contractile strain (Sa) decreased with increasing LAE.
  • Severe LAE showed significantly lower Stot and Sa compared to normal LA size.
  • In subjects with normal LA size, hypertension was associated with reduced Stot and conduit strain (Se).

Conclusions:

  • Left atrial phasic function remodeling occurs before LAE.
  • This remodeling process continues as LAE progresses.
  • Reservoir, conduit, and contractile functions are affected during this remodeling process.