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Asymptomatic choroid plexus carcinoma in an infant: Report of one case
Mohammed Moutaz Alshaghel1,2, Wafik Mayo1,3, Najeeb Sakkal4
1Faculty of Medicine, University of Aleppo, Aleppo, Syria.
Insights
Choroid Plexus Carcinoma (CPC) is a rare pediatric brain tumor with a poor prognosis. Early diagnosis and treatment are crucial for improving outcomes in affected children.
Area of Science:
- Pediatric neuro-oncology
- Neurosurgery
- Neuropathology
Background:
- Choroid Plexus Carcinoma (CPC) is a rare malignant brain neoplasm originating from the choroid plexus epithelium.
- This tumor predominantly affects infants and young children, often under two years of age.
- Common symptoms include nausea, vomiting, headache, irritability, blurred vision, and seizures, indicating potential neurological compromise.
Introduction:
Choroid Plexus Carcinomas (CPC) are rare malignant brain neoplasms of choroid plexus epithelium, with a tendency to occur in infants and children, especially those who are under two years of age. The Main symptoms of CPC include nausea, vomiting, headache, irritability, blurred vision, and seizures. Few studies discuss the therapeutic methods to treat this tumor. However, most of these studies confirmed the poor prognosis of it.
Case Presentation:
A two-year-old girl presented with a headache due to head trauma, normal consciousness, GCS 15/15, and without intracranial hypertension symptoms. Computed Tomography (CT) has shown a large heterogeneous lesion in the region of the right lateral ventricle. Magnetic resonance imaging (MRI) showed a large poorly-defined mass in the right lateral ventricle with mild dilatation of the ipsilateral lateral ventricle, and midline shift and marked edema surrounding it. In this case, the mass has been discovered by accident. The histological diagnosis was choroid plexus carcinoma (WHO grade 3), curettage of the right lateral ventricle was performed.
Discussion And Conclusion:
CPC is a serious condition with a poor prognosis. Early diagnosis and appropriate approaches are required in order to reduce mortality and morbidity rates.
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