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Updated: Sep 22, 2025

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Ye's Swing Technique for Small-incision Lenticule Extraction Surgery
Published on: June 27, 2025
138
Applying Information Gain to Explore Factors Affecting Small-Incision Lenticule Extraction: A Multicenter
Shuang Liang1, Shufan Ji2, Xiao Liu2
1Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.
Frontiers in Medicine
|May 20, 2022
Summary
Small-incision lenticule extraction (SMILE) is safe and effective for myopia correction. Key factors influencing postoperative refraction include preoperative corneal curvature, central corneal thickness, and residual stromal thickness.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Small-incision lenticule extraction (SMILE) is a popular refractive surgical procedure.
- Understanding factors influencing postoperative outcomes is crucial for optimizing patient results.
Purpose of the Study:
- To identify key factors affecting postoperative refraction after SMILE.
- To analyze the influence of preoperative and intraoperative variables on refractive outcomes.
Main Methods:
- Retrospective analysis of 2,350 eyes from 1,200 patients undergoing SMILE.
- Utilized information gain to assess the importance of various predictive factors.
- Collected anterior segment data including corneal curvature and central corneal thickness (CCT).
Main Results:
- SMILE demonstrated high safety and efficacy indices across three centers.
- Postoperative refraction showed significant correlations with preoperative spherical diopter, SE, maximum lenticule thickness, and CCT.
- Key influencing factors identified by information gain were preoperative mean anterior corneal curvature, CCT, refraction, and residual stromal thickness.
Conclusions:
- SMILE is a safe and effective procedure for myopia correction.
- Preoperative corneal characteristics and refractive error are significant predictors of postoperative refraction after SMILE.

