Recent progress of metal nanoclusters in electrochemiluminescence

Metal nanoclusters (MeNCs), composed of a few to hundreds of metal atoms and appropriate surface ligands, have attracted extensive interest in the electrochemiluminescence (ECL) realm owing to their molecule-like optical, electronic, and physicochemical attributes and are strongly anticipated for discrete energy levels, fascinating electrocatalytic activity, and good biocompatibility. Over the past decade, huge efforts have been devoted to the synthesis, properties, and application research of ECL-related MeNCs, and this field is still a subject of heightened concern. Therefore, this perspective aims to provide a comprehensive overview of the recent advances of MeNCs in the ECL domain, mainly covering the emerged ECL available MeNCs, unique chemical and optical properties, and the general ECL mechanisms. Synthesis strategies for desirable ECL performance are further highlighted, and the resulting ECL sensing applications utilizing MeNCs as luminophores, quenchers, and substrates are discussed systematically. Finally, we anticipate the future prospects and challenges in the development of this area.