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Prevalence of ocular lesions in cats newly diagnosed with histoplasmosis: 55 cases (2015-2022)
Jonathan D Pucket1, Katelyn E Fentiman2, Emily S McCool2
11Oklahoma Veterinary Specialists, Tulsa, OK.
Objective:
To describe the prevalence of ocular lesions in cats with newly diagnosed histoplasmosis.
Animals:
55 client-owned domestic cats.
Procedures:
As part of this prospective case series, cats diagnosed with histoplasmosis between the years 2015 and 2020 underwent complete ophthalmic examinations by a board-certified veterinary ophthalmologist prior to the initiation of antifungal treatment. Histoplasmosis was diagnosed by consistent clinical findings and identification of Histoplasma yeast on pathology or by the use of a commercially available enzyme immunoassay to detect Histoplasma antigen in urine.
Results:
Of the 55 cats, 45 (82%; 95% CI, 72% to 92%) had signs of active anterior, posterior, or panuveitis. The most common lesions were identified in the posterior portion of the globe and included chorioretinitis and partial retinal detachments (44/55 [80%; 95% CI, 69% to 90%] cats).
Clinical Relevance:
Detailed ophthalmic examinations should be performed on all cats with diagnosed or suspected histoplasmosis, as ocular involvement and subsequent vision loss are common.

