Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Muscle-Mimetic Core-Sheath Composite Yarn Scaffold for In-Body Tissue Induction and Regeneration of Small-Diameter Vascular Grafts.

Advanced healthcare materials·2026
Same author

Plant-derived extracellular vesicles for drug delivery: current and future.

Regenerative biomaterials·2026
Same author

Zhi-Zi-Chi Decoction Alleviates Depressive-like Behaviors by Regulating Gut Microbiota and Targeting the AMPK/PI3K-TOR Pathway via Its Metabolite Protocatechuic Acid.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Towards practical aqueous zinc metal pouch cell batteries via weakly bound water-mediated shear-thickening electrolyte.

Nature communications·2026
Same author

Active Constituents and Mechanisms of Xinshubao Tablets in Coronary Vasorelaxation.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Application and Molecular Modification of Enzyme in Textile Degumming.

Applied biochemistry and biotechnology·2026

Related Experiment Video

Updated: Sep 22, 2025

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers
09:54

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers

Published on: November 19, 2015

10.9K

A smart microhydrogel membrane sensor realized by pipette tip.

Yansheng Li1, Peng Chen2, Guowei Gao1

  • 1Beijing Key Laboratory for Sensors, Beijing Information Science & Technology University, Beijing, 100192, PR China; Key Laboratory of Modern Measurement and Control Technology, Ministry of Education, Beijing Information Science and Technology University, Beijing, 100192, PR China.

Biosensors & Bioelectronics
|May 20, 2022
PubMed
Summary
This summary is machine-generated.

Researchers developed a simple method to create thin hydrogel membranes using pipette tips. This technique also enabled the one-step fabrication of hydrogel sensors for sensitive potassium ion detection.

Keywords:
Gas pressure differenceHydrogel membranePortable sensorSmart molecules

More Related Videos

Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation
07:28

Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation

Published on: November 4, 2021

3.0K
Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration
09:29

Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration

Published on: January 19, 2020

8.6K

Related Experiment Videos

Last Updated: Sep 22, 2025

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers
09:54

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers

Published on: November 19, 2015

10.9K
Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation
07:28

Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation

Published on: November 4, 2021

3.0K
Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration
09:29

Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration

Published on: January 19, 2020

8.6K

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Analytical Chemistry

Background:

  • Hydrogel membranes are crucial in various applications, but their preparation often requires specialized equipment and complex processes.
  • Developing simple, controllable, and cost-effective methods for hydrogel membrane fabrication is essential for broader technological adoption.

Purpose of the Study:

  • To present a straightforward and practical method for fabricating hydrogel membranes with controlled thickness using a pipette tip.
  • To demonstrate the one-step fabrication of a hydrogel membrane sensor for rapid and sensitive ion detection.

Main Methods:

  • Utilized a pipette to generate a gas pressure difference, driving a gel precursor through a conical channel (pipette tip).
  • Leveraged the principle of decreasing radius in the tapered channel to control the thinning and thickness of the hydrogel membrane.
  • Incorporated smart molecules into the hydrogel precursor to create a functional sensor.

Main Results:

  • Successfully prepared hydrogel membranes with a controllable minimum thickness of 130 μm.
  • Fabricated a hydrogel membrane sensor capable of rapid and sensitive detection of potassium ions across a wide concentration range (0.5 μM–500 mM).
  • The developed method demonstrated high gel utilization and simple control over membrane thickness.

Conclusions:

  • The described method offers a practical, equipment-independent approach for hydrogel membrane and sensor fabrication.
  • This technique holds significant potential for advancing intelligent hydrogel-based analytical technologies due to its simplicity, controllability, and efficiency.
  • The fabricated hydrogel membrane sensor showcases broad applicability in analytical chemistry and sensing technologies.