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Immune-based therapeutic approaches in COVID-19
Aysan Moeinafshar1, Niloufar Yazdanpanah2, Nima Rezaei3
1School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Summary
This review explores immune-based therapies for COVID-19, examining treatments like corticosteroids and monoclonal antibodies. It highlights the immune system
Area of Science:
- Immunology
- Virology
- Infectious Diseases
Background:
- Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, was declared a pandemic by the WHO in March 2020.
- While risk reduction and vaccination are key, diverse treatments are being developed.
- The immune system's dual role in pathogen elimination and causing complications like cytokine storm syndrome makes it a therapeutic target.
Purpose of the Study:
- To conduct a comprehensive review of immune-based therapeutic strategies for COVID-19.
Main Methods:
- Literature review of immune-based treatments for COVID-19.
- Analysis of therapeutic approaches including corticosteroids, IVIG, interferon therapy, and anti-SARS-CoV-2 monoclonal antibodies.
Main Results:
- Immune-based therapies are a significant area of COVID-19 research.
- Various immune-modulating agents and specific antibody treatments have been investigated.
Conclusions:
- Immune-based approaches offer potential for managing COVID-19.
- Further research into these therapies is warranted to combat the disease effectively.
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