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Stable Isotopic Profiling of Intermediary Metabolic Flux in Developing and Adult Stage Caenorhabditis elegans
Published on: February 27, 2011
CeCaFLUX: the first web server for standardized and visual instationary 13C metabolic flux analysis
Zhentao Liu1,2, Zhengdong Zhang1,3, Sheng Liang3
1Key Laboratory of Information and Computing Science Guizhou Province, Guizhou Normal University, Guiyang, Guizhou, China.
Summary:
The number of instationary 13C-metabolic flux (INST-MFA) studies grows every year, making it more important than ever to ensure the clarity, standardization and reproducibility of each study. We proposed CeCaFLUX, the first user-friendly web server that derives metabolic flux distribution from instationary 13C-labeled data. Flux optimization and statistical analysis are achieved through an evolutionary optimization in a parallel manner. It can visualize the flux optimizing process in real-time and the ultimate flux outcome. It will also function as a database to enhance the consistency and to facilitate sharing of flux studies.
Availability And Implementation:
CeCaFLUX is freely available at https://www.cecaflux.net, the source code can be downloaded at https://github.com/zhzhd82/CeCaFLUX.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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