Related Experiment Video
Updated: Sep 22, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Combinatorial Self-Assembly of Coordination Cages with Systematically Fine-Tuned Cavities for Efficient
Shao-Chuan Li1,2, Li-Xuan Cai1,2, Maochun Hong1,2
1State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002 (P. R., China.
Abstract:
Controllable arrangement of different ligands in a single assembly will not only bring increased complexity but also offers a new route to fine-tune the function of the designed architecture. We report here a combinatorial self-assembly with enPd(NO3 )2 and three different ligands (L1-3 ), which gave rise to a family of six palladium-organic cages (C1-6) with systematically varied shapes and cavities, including three new heteroleptic (Pd5 L1 2 L2 , Pd5 L1 2 L3 , Pd4 L2 L3 ), one new homoleptic (Pd4 L3 2 ) cages, and two known homoleptic (Pd6 L1 4 , Pd4 L2 2 ) cages. Emergent functions due to the fusion of two half cavities on the heteroleptic cages from their parent homoleptic cages have been observed: the heteroleptic cages can form ternary complexes by co-encapsulation of both aromatic and aliphatic guests, while their homoleptic counterparts can only form binary complexes. Such a forced co-encapsulation effect endows the heteroleptic cages with enhanced catalytic power for the Knoevenagel condensation.
More Related Videos
10:01Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
Published on: April 8, 2020
09:34Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment
Published on: July 12, 2016
Related Concept Videos
Assembly of Cytoskeletal Filaments
COP Coated Vesicles
Protein Complex Assembly
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Clathrin Coated Vesicles
Assembly of Signaling Complexes
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...