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MR elastography is a good response parameter for microwave ablation liver tumors
Thomas J Vogl1, Max P Dosch1, Yannick Haas2
1Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany.
European Journal of Radiology
|May 21, 2022
Summary
MR elastography (MRE) can assess liver tissue response to microwave ablation (MWA) of tumors. Higher baseline tumor stiffness requires more MWA energy and longer duration for effective treatment.
Area of Science:
- Hepatology
- Oncology
- Radiology
Background:
- Percutaneous microwave ablation (MWA) is a common treatment for liver tumors.
- Assessing treatment response and collateral tissue damage after MWA is crucial.
Purpose of the Study:
- To evaluate the utility of MR elastography (MRE) in assessing hepatic tissue response to MWA for liver tumors.
- To correlate MRE findings with MWA parameters and treatment outcomes.
Main Methods:
- 51 patients with liver tumors underwent MWA, with MRI and MRE performed before and 24 hours after the procedure.
- Retrospective analysis included tumor characteristics, MRE stiffness values, and MWA parameters (duration, energy dose).
Main Results:
- Total liver stiffness increased post-MWA, correlating with MWA session duration.
- Higher baseline tumor stiffness required increased MWA energy and duration.
- Healthy parenchyma stiffness was influenced by cumulative energy, duration, and energy intensity.
- Successful ablations were associated with increased ablation margin stiffness and higher ablation intensity.
Conclusions:
- MRE can be a valuable tool for assessing treatment response and collateral tissue damage post-MWA.
- Baseline tumor stiffness is a key factor in determining appropriate MWA parameters.
