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Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) and esophageal rupture by candida infection:
Maurício Domingues-Ferreira1, Dewton de Moraes Vasconcelos1, Thiago de Almeida Bezerra1
1Outpatient clinic for cutaneous manifestations of primary immunodeficiencies in the dermatology department of Hospital das Clinicas, Faculty of Medicine, University of São Paulo. São Paulo, Brazil.
Abstract:
We probably describe the first report of esophageal rupture in a patient with autoimmune polyendocrinopathy - candidiasis - ectodermal dystrophy (APECED, OMIM # 240300), who had candida esophagitis as the main feature for decades. Strong evidence shows that this rupture may have been caused directly and indirectly by chronic candidiasis. In this way, we demonstrate how severe and harmful the persistent esophageal candidiasis can cause in the esophagus, especially in immunodeficient patients.
