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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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Application of physiologically based absorption and pharmacokinetic modeling in the development process of oral

Saima Subhani1, Chaejin Kim1, Paula Muniz2

  • 1Center for Pharmacometrics and System Pharmacology at Lake Nona (Orlando), Department of Pharmaceutics, College of Pharmacy, University of Florida, FL, USA.

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
|May 22, 2022
PubMed

Keywords:
In vitro- in vivo correlations (IVIVC)Mechanistic absorption modelingMechanistic modelingModeling and simulationModified release drug productsOral generic drug productsPhysiologically based pharmacokinetic (PBPK) modeling for biopharmaceutics applications

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