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Updated: Sep 22, 2025

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery
Published on: October 6, 2022
Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene
Ami Aoki1, Akira Saito1, Kenjiro Shima1
1Department of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Japan.
Abstract:
We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory infection. The patient's occupation for 26 years involved spraying PTFE. A lung biopsy using bronchoscopy revealed granulomatous lesions and giant cells. The presence of fluorine in the granulomatous lesions was confirmed using an electron probe microanalyzer with wavelength dispersive spectrometer. Fluorine is a component of PTFE and is not found in normal lung tissue.
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