Related Experiment Video
Updated: Sep 22, 2025
Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
Optical coherence tomography findings of cyanoacrylate glue patch in corneal perforations
Eduardo J Polania-Baron1, Eduardo Gonzalez-Lubcke1, Enrique O Graue-Hernandez1
1Department of Cornea, External Diseases and Refractive Surgery, Institute of Ophthalmology "Conde de Valenciana", Mexico City, Mexico.
Purpose:
To report a cases series of corneal perforations treated with cyanoacrylate glue patch (CGP) assessed with optical coherence tomography for monitoring corneal status in long-term follow-up examinations.
Observations:
CPG was successfully used as primary treatment in three cases of corneal perforations. Spontaneous loosening or dislodging of the CPG did not occur in the follow-up. Anterior segment optical coherence tomography (AS-OCT) was performed to monitor wound healing at the site of perforation before considering the CGP removal. The presence of normal epithelium layer beneath the glue patch and stromal regeneration tissue were confirmed by AS-OCT, and glue patch was safely removed.
Conclusions And Importance:
The area of healing tissue beneath the CGP may not be easy to evaluate using the slit-lamp microscopy alone. AS-OCT is a useful tool in the assessment of corneal healing tissue in the presence of cyanoacrylate glue patch.
