Related Experiment Video
Updated: Aug 3, 2026
07:07
Inducing Post-Traumatic Epilepsy in a Mouse Model of Repetitive Diffuse Traumatic Brain Injury
Published on: February 10, 2020
10.7K
Epilepsy associated tuberous sclerosis; a case report from Bangladesh
Abhigan Babu Shrestha1, Sajina Shrestha2, Senjuti Seemanta1
1Department of Internal Medicine, M Abdur Rahim Medical College, Dinajpur, Bangladesh.
Annals of Medicine and Surgery (2012)
|May 23, 2022
Summary
Tuberous sclerosis, a rare genetic disorder, affects multiple organs and often presents symptoms later in childhood. This case highlights a 15-year-old female diagnosed with this complex condition.
Area of Science:
- Genetics and rare diseases
- Neurology
- Dermatology
Background:
- Tuberous sclerosis (Bourneville's disease) is an autosomal dominant disorder.
- It affects multiple organs including the brain, heart, lungs, eyes, kidneys, and skin.
- Characterized by neurological issues like epilepsy, skin changes, and benign tumors.
Observation:
- Symptoms typically manifest in late childhood, complicating early diagnosis in infants.
- A case study of a 15-year-old female with tuberous sclerosis is presented.
- The patient exhibited symptoms consistent with the disease's multi-organ involvement.
Findings:
- The diagnosis was confirmed in a 15-year-old female.
- The case illustrates the typical presentation of tuberous sclerosis in adolescence.
- Analysis of the case provides insights into the disease's progression and diagnostic challenges.
Implications:
- Early diagnosis in infancy remains a challenge due to late-onset symptoms.
- This case contributes to understanding the varied clinical manifestations of tuberous sclerosis.
- Further research is needed to improve early detection and management strategies for this rare disease.
More Related Videos
Related Concept Videos
01:24Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
01:13Seizures: Classification
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
01:19Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
01:20Seizures l: Introduction
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
01:19Seizures ll: Types
Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
01:22Epilepsy ll: Types
Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.