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Updated: Sep 22, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
Published on: July 27, 2021
Ultra-fine transformation of data for normality
Mohammad M Hamasha1, Haneen Ali2, Sa'd Hamasha3
1Department of Industrial Engineering, Faculty of Engineering, The Hashemite University, B.O.Box 330127, Zarqa 13313, Jordan.
Abstract:
Normally distributed data is crucial for the application of large-scale statistical analysis. To statisticians, the most important assumptions of statistical users are the adequacy of the data and the normal distribution of the data. However, users are constantly forced to deal with unusual data. This includes changing the method used to be less sensitive to non-normal data or transforming that data to normal data. In addition, common mathematical transformation methods (for example, Box-Cox) do not work on complex distributions, and each method works on limited data shapes. In this paper, a novel approach is presented to transform any data into normally distributed data. We refer to our approach as the Ultra-fine transformation method. The article's novelty is that the proposed approach is powerful enough to accurately transform any data with any distribution to the standard normal distribution. Besides this approach's usefulness, it is simple in both theory and in application, and users can easily retrieve the original data from its transformed state. Therefore, we recommend using this method for the data used in the statistical method, even if the data are normal.
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