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Updated: Sep 22, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
COVID-19 severity: A new approach to quantifying global cases and deaths
Daniel L Millimet1, Christopher F Parmeter2
1Department of Economics Southern Methodist University Dallas Texas USA.
Abstract:
As the COVID-19 pandemic has progressed, so too has the recognition that cases and deaths have been underreported, perhaps vastly so. Here, we present an econometric strategy to estimate the true number of COVID-19 cases and deaths for 61 and 56 countries, respectively, from 1 January 2020 to 3 November 2020. Specifically, we estimate a 'structural' model based on the SIR epidemiological model extended to incorporate underreporting. The results indicate significant underreporting by magnitudes that align with existing research and conjectures by public health experts. While our approach requires some strong assumptions, these assumptions are very different from the equally strong assumptions required by other approaches addressing underreporting in the assessment of the extent of the pandemic. Thus, we view our approach as a complement to existing methods.
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