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Engineering multifunctional bioactive citrate-based biomaterials for tissue engineering.

Min Wang1, Peng Xu1, Bo Lei2,3,4,5

  • 1Honghui Hospital, Xi'an Jiaotong University, Xi'an, 710000, China.

Bioactive Materials
|May 23, 2022
PubMed
Summary
This summary is machine-generated.

Citrate-based polymers offer tunable, bioactive properties for regenerative medicine. This review highlights their diverse applications and future potential in advanced biomedical uses.

Keywords:
Bioactive materialsBioactive polymersCitrate-based biomaterialsMultifunctional modificationTissue engineering

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Regenerative Medicine

Background:

  • Bioactive biomaterials are essential for regenerative medicine.
  • Citrate-based polymers are a unique class of bioactive biomaterials due to their synthesis, structure, biocompatibility, and mechanical properties.
  • These polymers offer functional groups for modification, enabling versatile applications.

Purpose of the Study:

  • To review recent advancements in the multifunctional design of citrate-based polymers.
  • To summarize the diverse biomedical applications of these polymers.
  • To discuss future directions for developing tailored citrate-based polymers.

Main Methods:

  • Literature review of recent studies on citrate-based polymers.
  • Analysis of multifunctional designs and biomedical applications.
  • Discussion of property tailoring for specific medical needs.

Main Results:

  • Citrate-based polymers have shown significant potential in various biomedical fields.
  • Applications include cardiovascular, orthopedic, muscle, skin, and nerve tissue engineering.
  • They are also explored for bioimaging and drug/gene delivery systems.

Conclusions:

  • Citrate-based polymers are promising for regenerative medicine due to their tunable properties.
  • Further development is needed to optimize their tailored characteristics for specific biomedical applications.
  • These materials hold considerable clinical application potential.