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Related Concept Videos

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Disorders of the Skeletal Muscle01:28

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
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Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act centrally to reduce muscle tone or spasms in painful conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or spinal injuries; they are called antispasmodics or spasmolytics.
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Updated: Sep 22, 2025

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
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Movement Disorders in Multiple Sclerosis: An Update.

Ritwik Ghosh1, Dipayan Roy2,3,4, Souvik Dubey5

  • 1Department of General Medicine, Burdwan Medical College & Hospital, Burdwan, West Bengal, India.

Tremor and Other Hyperkinetic Movements (New York, N.Y.)
|May 23, 2022
PubMed
Summary
This summary is machine-generated.

Multiple sclerosis (MS) is linked to various movement disorders, impacting diagnosis and management. Understanding these conditions is crucial for effective, multidisciplinary treatment strategies.

Keywords:
ataxiachorea/ballismdystoniamovement disordersmultiple sclerosismyoclonusparkinsonismrestless leg syndrometicstremor

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Area of Science:

  • Neurology
  • Neuroimmunology
  • Movement Disorders

Background:

  • Multiple sclerosis (MS) is a central nervous system inflammatory demyelinating disease.
  • MS is frequently associated with diverse movement disorders, stemming from disease pathophysiology or co-occurrence.

Purpose of the Study:

  • To review the spectrum of movement disorders in multiple sclerosis.
  • To explore potential mechanistic pathways and therapeutic options for these movement disorders.

Main Methods:

  • A narrative literature review was performed.
  • Searches included 'multiple sclerosis' and specific movement disorders in PubMed up to October 2021.

Main Results:

  • Common movement disorders in MS include restless leg syndrome, tremor, ataxia, parkinsonism, and dyskinesias.
  • Clinical and neuroimaging data support the association between these disorders and MS.
  • Treatments are disorder-specific, often requiring a multidisciplinary approach (pharmacological, surgical, physical therapy).

Conclusions:

  • Movement disorders in MS involve complex pathophysiological processes and anatomical pathways.
  • These symptoms can aid in early MS diagnosis and disease progression monitoring.
  • Further research is needed to elucidate prevalence and underlying mechanisms of MS-related movement disorders.