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Related Experiment Video

Updated: Sep 22, 2025

Author Spotlight: Eco-Friendly Extraction of Bioactive Compounds Using Polyol-Based Microwave-Assisted Techniques
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Phlorotannins-bioactivity and extraction perspectives.

Lekshmi R G Kumar1, Preethy Treesa Paul1, K K Anas1

  • 1ICAR-Central Institute of Fisheries Technology (CIFT), Cochin-29, Cochin, India.

Journal of Applied Phycology
|May 23, 2022
PubMed
Summary
This summary is machine-generated.

Seaweed-derived phlorotannins exhibit diverse health benefits, including antioxidant and anti-inflammatory properties. Further research and consumer awareness are needed for their commercialization as nutraceuticals.

Keywords:
Anti-proliferativeAnti-viralHistamineHyaluronidaseLipopolysaccharideMelanosisNeurodegenerationNitric oxidePhloroetholsSupercritical fluid extraction

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Area of Science:

  • Marine Natural Products Chemistry
  • Phytochemistry
  • Pharmacology

Background:

  • Phlorotannins are polyphenolic compounds found in brown seaweeds.
  • They possess a wide range of potential bioactivities, including antioxidant, antimicrobial, anti-inflammatory, and anti-diabetic effects.
  • Growing interest in these compounds drives the exploration of sustainable extraction methods.

Purpose of the Study:

  • To review the extraction methods and bioactivities of phlorotannins.
  • To highlight the potential of phlorotannins as nutraceutical ingredients.
  • To underscore the need for consumer awareness and advanced analytical techniques for commercialization.

Main Methods:

  • Review of in vivo and in vitro studies on phlorotannin extraction and bioactivities.
  • Exploration of sustainable extraction techniques like supercritical fluid extraction, microwave-assisted extraction, and enzyme-assisted extraction.
  • Discussion of analytical techniques such as mass spectrometry and 1H-NMR spectroscopy for quantification.

Main Results:

  • Phlorotannins demonstrate significant antioxidant, antimicrobial, anti-allergic, anti-diabetic, anti-inflammatory, anti-cancerous, and neuroprotective properties.
  • Various sustainable extraction methods are being investigated for efficient phlorotannin isolation.
  • Accurate quantification is crucial for commercialization due to structural diversity.

Conclusions:

  • Phlorotannins hold considerable promise as bioactive compounds for nutraceutical applications.
  • Advancements in extraction and analytical techniques are essential for industrial-scale production and commercialization.
  • Increased consumer awareness regarding the physiological benefits of phlorotannins is vital for market development.