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Poly(pseudo)rotaxanes formed by mixed micelles and α-cyclodextrin enhance terbinafine nail permeation to deeper

Anna Paula Krawczyk-Santos1, Ricardo Neves Marreto1, Angel Concheiro2

  • 1Laboratory of Nanosystems and Drug Delivery Devices (NanoSYS), School of Pharmacy, Universidade Federal de Goiás (UFG), Rua 240, Setor Leste Universitário, 74, 605-170 Goiânia, GO, Brazil.

International Journal of Pharmaceutics: X
|May 23, 2022
PubMed

Keywords:
CDs, cyclodextrinsGEL, Gelucire® 48/16Mixed micellesNail permeationOnychomycosisPEG, polyethylene glycolPPR, poly(pseudo)rotaxanePdI, polydispersity indexPoly(pseudo)rotaxanesRH40, Kolliphor® RH40RH40:GEL, mixture of RH40 and GEL 1:1Supramolecular gelsTB, terbinafine hydrochlorideTerbinafine

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