Pretransplant assays of alloimmunity in predicting renal graft outcome

Forty-one renal allograft recipients were studied for evidence of specific antidonor alloimmunity prior to transplantation. Pretransplant evidence of antibody to the donor as detected by ADCC correlated with the occurrence of early graft loss. This suggests that the ADCC may serve as a useful pretransplant corssmatching procedure.