Related Experiment Videos
Long-term results of renal transplantation in children
Proceedings of the Clinical Dialysis and Transplant Forum
|January 1, 1977
Insights
Outcomes for pediatric renal allograft recipients are positive, with most children surviving with functioning kidneys and engaging in age-appropriate activities, despite growth challenges.
Area of Science:
- Pediatric nephrology
- Transplantation immunology
- Pediatric surgery
Background:
- Renal allograft transplantation is a critical treatment for children with end-stage renal disease.
- Long-term outcomes and quality of life in pediatric transplant recipients require ongoing evaluation.
- Growth and development are key concerns following pediatric transplantation.
Purpose of the Study:
- To assess the survival and allograft function rates in children who received renal allografts.
- To evaluate the long-term rehabilitation and activity levels of pediatric renal transplant recipients.
- To identify persistent challenges, such as growth retardation, in this population.
Main Methods:
- Retrospective analysis of 81 children at risk following initial renal allograft.
- Data collection on patient survival, allograft function, and engagement in age-appropriate activities.
- Assessment of growth patterns and rehabilitation status post-transplantation.
Main Results:
- 62 out of 81 (77%) children are alive at follow-up.
- 54 out of 81 (67%) have a functioning renal allograft.
- 94% of surviving recipients with functioning allografts are engaged in age-appropriate activities, indicating excellent rehabilitation despite growth issues.
Conclusions:
- Pediatric renal allograft transplantation offers significant survival benefits.
- While growth retardation persists as a challenge, successful rehabilitation and high levels of activity are achievable.
- The study highlights the importance of comprehensive post-transplant care focusing on both medical and developmental outcomes.
Abstract:
Of 81 children at risk for 5 to 11 yrs following an initial renal allograft, 62 (77%) are alive and 54 (67%) have a functioning allograft. Growth retardation remains a significant problem following transplantation in children; however, rehabilitation is excellent with 94% of recipients surviving with a functioning allograft engaged in age appropriate activities.